What is true regarding mechanical valves compared to biological valves?

Mechanical valves are designed for long-term use and exhibit greater durability compared to biological valves, which typically have a limited lifespan that may necessitate replacement after a certain period, usually around 10-20 years depending on various factors, including the patient's age and health condition.

One of the key considerations when using mechanical valves is the need for lifelong anticoagulation therapy. This is pivotal because mechanical valves have a tendency to create turbulence in the blood flow, which can increase the risk of thrombosis (blood clots). The anticoagulants, such as warfarin, are essential to minimize this risk and ensure proper blood flow through the valve.

In contrast, biological valves, made from animal tissues, tend to integrate better with the patient's own tissue, which may reduce the likelihood of clot formation and may necessitate less aggressive anticoagulation strategies. However, they can still require anticoagulation on a temporary basis or in specific clinical scenarios.

Thus, the statement regarding the requirement for lifelong anticoagulation when using mechanical valves is fundamentally accurate and reflects a crucial aspect of the management of patients who have undergone valve replacement surgery with these devices.